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Omega-3 Helps Reduce Brain Inflammation

Dr. Russell Blaylock, M.D., writes:

Virtually all neurodegenerative disorders are the result of low-grade brain inflammation triggered by activation of the brain’s main immune cells — called microglia. These cells are normally in what is called a “resting” state. But actually, they are quite active, mainly making repairs and removing debris that has collected in the brain as cells die off.

It’s a continuous cleanup operation. When activated, these microglia release an assortment of inflammatory factors (cytokines, chemokines, and interferons) as well as glutamate (the excitatory amino acid) into the fluid space outside brain cells. Combined with inflammation, this causes a very destructive process I have termed immunoexcitotoxicity.

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Immunoexcitotoxicity occurs with all neurodegenerative diseases, as well as in strokes, trauma, autoimmune diseases, and infections of the central nervous system. It is an ongoing process that lasts for a very long period and accelerates destruction.

Sometimes the immune reaction in the brain and spinal cord is much more intense and rapidly occurring, with greater destruction over a short period of time — as we see with some autoimmune diseases as well as encephalitis.

A number of studies have shown that DHA significantly reduces the destructive effects of neurodegenerative diseases. The most popular forms of DHA are the ethyl ester DHA and triglyceride DHA. Newer studies found that triglyceride DHA was far more effective for lowering inflammatory cytokines and reducing nervous system damage.

After Alzheimer’s, the second most common neurodegenerative disease is Parkinson’s. One of the primary destructive factors in Parkinson’s disease is a loss of mitochondrial energy production. Along with reducing brain inflammation, omega-3 oils increase mitochondrial energy production.

DHA has also been shown to reduce some of the complications of the Parkinson’s drug L-DOPA (levodopa), including dyskinesia (abnormality or impairment of voluntary movement).

Omega-3 oils have also been shown to reduce the damage to cells in the brain’s substantia nigra, the site of most Parkinson’s destruction.

An additional benefit of supplementing with omega-3 oils is reducing depression and cognitive decline, both of which are common problems seen in Parkinson’s patients.

Dr. Russell Blaylock, M.D., is editor of The Blaylock Wellness Report and a nationally recognized board-certified neurosurgeon, health practitioner, author, and lecturer.

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Discover 'The Magnesium Miracle'


Many people have heard of coenzyme Q10 (CoQ10), but don’t really understand the crucial role it plays in health.

CoQ10 is a natural, vitamin-like substance found in body cells, particularly in organs with higher energy needs — like the heart.

All cells contain mitochondria, microscopic “powerhouses” that generate life-giving energy. CoQ10 plays a vital part in this energy production process.

In addition to enhancing cellular energy production in the heart, brain, and other organs, CoQ10 provides additional benefits. During energy production, cell-damaging free radicals are formed as byproducts of this oxidation process. And as a powerful antioxidant, CoQ10 helps counteract this oxidative stress, further supporting the health of cells in the heart and other organs.

Research also indicates that CoQ10 helps promote the health of the endothelium, or inner lining of blood vessels. This is important to cardiovascular health because it supports normal circulation and balanced inflammation.

Aging Adults & Statin Users Need More CoQ10

Unfortunately, CoQ10 levels decrease with age. In fact, CoQ10 levels are highest in the first 20 years of life, but decline gradually after that point. By the fourth decade, CoQ10 levels may have dropped as much as 30%.

Statin drugs used for cholesterol also deplete natural levels of CoQ10. Because of these issues, renowned cardiologist Dr. Chauncey Crandall decided to work with experts at the premium supplement company Medix Select to develop the advanced formula COTREXIN® with CoQ10.

Why Most CoQ10 Is a Waste of Money

Many traditional CoQ10 supplements provide less than 200 mg a day of CoQ10, so they are unlikely to deliver significant cardiac benefits. In addition, typical CoQ10 is very poorly absorbed by the body.

The reason most CoQ10 is poorly absorbed is because it is insoluble in water and soluble in oil. With the body being up to 60% water, most of the CoQ10 doesn’t dissolve and is excreted in the urine — literally flushed away.

That’s why Dr. Crandall added BioPerine® black pepper fruit extract to COTREXIN. This patented nutrient increases absorption levels and bioavailability by up to 30%.

And unlike many typical supplements, COTREXIN offers a full 200 mg of CoQ10 per daily serving of two capsules. But Dr. Crandall didn’t stop there. He added another ingredient to the COTREXIN formula.

COTREXIN Includes Omega-3s for
Added Cardio Support

COTREXIN contains 850 mg of omega-3s per daily serving, with 650 mg of EPA and 100 mg of DHA.

Scientific research has shown that omega-3s found in fish oil, including EPA and DHA, promote heart health and normal cholesterol. Omega-3s also promote normal inflammatory balance. In addition, DHA supports brain health.

The Dynamic Duo for Powerful
Heart Health Support

COTREXIN with CoQ10 and omega-3s makes it easy to help support the entire cardiovascular system. Try COTREXIN today!

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9 Health Benefits of
Doctor-Developed COTREXIN®

  1. Supports Heart Health and Function
  2. Supports Brain Health
  3. Enhances Cellular Energy Production
  4. Supports Normal Blood Pressure Levels
  5. Supports Circulatory Health
  6. Promotes Healthy Inflammatory Response
  7. Supports Antioxidant Activity
  8. Supports Healthy Triglyceride Levels
  9. Helps Reduce the Oxidation of Cholesterol

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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Trial requires enrollment in the SmartShip program, terms and conditions apply. Please call or view our website for complete details. All information presented above is for informational purposes only, and is not specifically applicable to any individual’s medical problem(s), concerns, and/or needs. Readers are advised to consult a health professional about any issue regarding their health and well-being. ©2025 Medix Health LLC. All rights reserved. Medix Select is a registered trademark of Medix Health LLC.