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Issue 1,814: May 21, 2025  
Top Stories
 
Immunize​.org Website and Clinical Resources 

Featured Resources
 
Notable Publications
 
Upcoming Events
 
Top Stories

HHS makes recent ACIP chikungunya virus vaccine recommendations official

On May 13, while awaiting confirmation of a new CDC Director, the HHS Secretary adopted the chikungunya vaccine recommendations made by the ACIP on April 16 (see Recent Meeting Recommendations; April 15–16, 2025). These are now official federal recommendations. They involve two distinct vaccines: live attenuated chikungunya vaccine (CHIK-LA, Ixchiq, Valneva) and the non-live virus-like particle chikungunya vaccine (CHIK-VLP, Vimkunya, Bavarian Nordic).

Important note: On May 9, FDA and CDC recommended not administering CHIK-LA (Ixchiq) to individuals age 60 years or older while an investigation of reported serious cardiac and neurologic adverse events following its use proceeds. This superseded the more limited ACIP recommendation made on April 16 for a precaution to the use of Ixchiq in people age 60 years and older.

The newly adopted recommendations involve two groups of people:

Laboratory workers: ACIP recommended use of CHIK-VLP (Vimkunya) for laboratory workers with potential for exposure to chikungunya virus. (Note: Ixchiq is already a recommended option for this population.)

Travelers: The two vaccines are recommended for different ages: only CHIK-VLP (Vimkunya) is approved for use in adolescents down to age 12 years.

  • ACIP recommended use of virus-like particle chikungunya vaccine (CHIK-VLP) for people age 12 years and older traveling to a country or territory where there is a chikungunya outbreak. CHIK-VLP vaccine also may be considered for people age 12 years and older traveling or taking up residence in a country or territory without an outbreak but with elevated risk for U.S. travelers if planning travel for an extended period, e.g., 6 months or more.
  • ACIP recommended use of live attenuated chikungunya vaccine (CHIK-LA) for people age 18 years and older traveling to a country or territory where there is a chikungunya outbreak. CHIK-LA vaccine also may be considered for people age 18 years and older traveling or taking up residence in a country or territory without an outbreak but with elevated risk for U.S. travelers if planning travel for an extended period, e.g., 6 months or more.

Now that they are official, the chikungunya vaccine recommendations will be published in MMWR and reflected in CDC’s print and digital resources in the coming months.

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Immunize​.org updates references in six more standing orders templates 

Immunize​.org updated six standing orders templates to remove the reference to the excipient table that used to appear in Appendix B of the Epidemiology and Prevention of Vaccine-Preventable Diseases (the "Pink Book"). The updated standing order templates include:

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Immunize​.org updates web link in “Vaccine Storage Troubleshooting Record” 

Immunize​.org updated a nonfunctioning URL in its Vaccine Storage Troubleshooting Record.

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Confirmed measles cases rise to 1,024 across 30 states

As of May 16, CDC reported 1,024 confirmed measles cases in 2025 in 30 states. Most (718 of 1,024, 70%) were reported by the Texas Department of State Health Services. Children and teens younger than age 20 years account for 68% of cases. Among confirmed cases, 13% have been hospitalized. It should be noted that CDC only requires reporting of laboratory-confirmed measles cases. Cases without laboratory testing for confirmation are not included in these numbers; actual numbers of cases are, therefore, expected to be higher than confirmed case counts.

A map of 2025 measles cases in the continental United States, as of May 16, from the Johns Hopkins Center for Outbreak Response Innovation (CORI) appears below. The CORI Measles Outbreak Response website offers various ways to visualize the outbreak.



CDC offers a suite of resources for public health, healthcare professionals, and families in communities experiencing a measles outbreak. Resources include infographics for families, images to help clinic personnel identify cases, and a Be Ready for Measles communication toolkit. A quick reference for healthcare professionals provides guidance for caring for patients with measles. Find all these resources on the CDC Measles Cases and Outbreaks page.



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Preparing yourself or others for travel? Use your smartphone to watch our 2-minute Orientation Video Series: “Introducing Travel Vaccines Information” (mobile view)

Learn how to navigate Immunize​.org’s travel vaccine information on the go with your smartphone. Check out the “mobile view” version of our 2-minute Orientation Video Series: Introducing Travel Vaccines Information.
 
The entire Orientation Video Series is available on our YouTube channel.

Share these videos with anyone who wants to learn more about effective immunization practices with Immunize.org.

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Vaccines in the news

These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.


Immunize​.org Website and Clinical Resources

Spotlight on the website: State Vaccine-Specific Requirements and Exemptions 

This week we spotlight two pages with important information for clinicians, public health authorities, vaccination advocates, and families: Vaccine-Specific Requirements by state and State Exemptions.

These can be found by choosing the Official Guidance tab atop each page, then selecting States from the left-hand list. 
 
Vaccine-Specific Requirements contains links to vaccine-specific requirements by state for daycare, school, and post-secondary education settings. Each vaccine listed on the page can be expanded to view links to each state’s requirements in a data table and as a downloadable map. State immunization program managers reported these data in May 2024. A link to view an archive of 2023 requirements is also available.



The State Exemptions page links to a data table and map showing which states accept medical, religious, and personal vaccination exemptions and a map of exemptions permitted for school and childcare. It also links to policy statements from medical organizations endorsing strong school and childcare vaccination requirements. Toward the top of the page is a link to view an archive of 2023 requirements.



Related Links


Featured Resources

ACOG releases season four of Labor of Love podcast discussing maternal vaccination and other topics

The American College of Obstetricians and Gynecologists (ACOG) is in its fourth season of its podcast series, Labor of Love. For the podcast’s fourth season, Supporting Maternal Well-Being in a Complex World, host Veronica Pimentel, MD, MS, and other obstetric care professionals discuss various topics, including, in Episode 2, Vaccinating for Two: Overcoming Challenges in Maternal Vaccines.
 


New episodes are released every other Thursday. 

Subscribe to Labor of Love on Spotify or Apple Podcasts.

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Public Health Communications Collaborative shares two sets of resources: communicating about Long COVID and addressing the importance of pediatric vaccines

The Public Health Communications Collaborative (PHCC) offers sharable resources on Long COVID and pediatric vaccines for communication with the public. Resources include:

  • Still Here: Communicating About Long COVID: Contains a guide with information about the lasting impact of SARS-CoV-2 infection and Long COVID, as well as messaging guidance for public health communicators, and social media graphics and captions for communication with the public on Long COVID
  • Communicating About the Importance of Pediatric Vaccines: Social media graphics, available in English and Spanish, to explain the importance of pediatric vaccines and help caregivers keep their children on track with recommended vaccines



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Vaccinate adults! Order laminated 2025 U.S. adult immunization schedule booklets.

Laminated booklets of the 2025 U.S. adult immunization schedule are still available in the Immunize​.org shop. The 2025 child and adolescent schedule booklets sold out.

The schedules are available online as PDFs from CDC at no cost. Immunize​.org’s laminated booklets are ideal for use in any busy healthcare setting where vaccines are given.


    
Pricing:

Adult Booklets
1 copy: $10.00
2–4 copies: $9.50 each
5–19 copies: $8.50 each
20–99 copies: $7.50 each
100–499 copies: $6.00 each
500–999 copies: $5.00 each
1,000–1,999 copies: $4.00 each
2,000+ copies: $3.25 each

Visit the Shop Immunize.org: Laminated Schedules web page to view images and order today!

For additional information, call 651-647-9009 or email [email protected].

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Assessing adults for vaccine needs? Use Immunize​.org’s Vaccinating Adults: A Step-by-Step Guide—free to download.

Download Immunize​.org’s free 142-page book on adult vaccination to help build your program and train your team: Vaccinating Adults: A Step-by-Step Guide (Guide).

 

This thorough "how to" guide on adult vaccination provides easy-to-use, practical information covering all essential activities. It helps vaccine providers enhance their existing adult vaccination services or introduce them into any clinical setting.

The Guide is available to download/print either by chapter or in its entirety free of charge. The National Vaccine Program Office and CDC both supported the development of the Guide and provided early technical review.

The Guide is a valuable resource to assist providers in increasing adult vaccination rates. Be sure to get a copy today!

Please note: this guide was produced in 2017, before the COVID-19 era, and reflects the recommendations of that time.

Related Links


Notable Publications

“Infant Respiratory Syncytial Virus Immunization Coverage in the Vaccine Safety Datalink: 2023–2024” and a corresponding commentary published in Pediatrics

In the May 6 issue, Pediatrics published Infant Respiratory Syncytial Virus Immunization Coverage in the Vaccine Safety Datalink: 2023–2024, along with a video abstract. Part of the abstract appears below.

Overall, 72% of infants were immunized against RSV; estimates were highest among infants born to non-Hispanic (NH) Asian mothers (84%). Disparities were identified by race, with 60% coverage among infants born to NH Black or NH Middle Eastern or North African mothers. Coverage was 59% to 78% by birth month, with nirsevimab more commonly administered to infants born earlier in the season.

RSV protection by maternal age group is shown below.



Related Link


No link found in study: "Coronavirus Disease 2019 (COVID-19) Vaccination and Spontaneous Abortion" published in Obstetrics and Gynecology

In the May 2 issue, Obstetrics and Gynecology published Coronavirus Disease 2019 (COVID-19) Vaccination and Spontaneous Abortion. Spontaneous abortion was defined as unintentional fetal loss between 6 and less than 20 weeks of gestation. Portions of the abstract appear below.

Matched analyses included 296 patients in the spontaneous abortion case group and 592 in the live birth control group. There was no association between spontaneous abortion and COVID-19 vaccination . . . There was also no association between spontaneous abortion and dose number compared with no vaccine [neither one dose nor two doses, nor by manufacturer] . . .

There was no observed association between COVID-19 vaccination in pregnancy and spontaneous abortion. Findings support the safety of COVID-19 vaccination in early pregnancy.


Upcoming Events

Virtual: National Academy of Medicine hosts webinar titled “Measles 2025: The State of the Outbreak” on May 27 at 4:00 p.m. (ET)

The National Academy of Medicine and partners will host a webinar titled Measles 2025: The State of the Outbreak at 4:00–5:30 p.m. (ET) on May 27. Amid the widespread and dangerous measles outbreak in the United States, healthcare providers, public health practitioners, and members of the public need to know how to protect their patients, communities, and loved ones. The webinar will cover:

  • How measles spreads and how it can be contained
  • Symptoms of measles and how it is diagnosed and treated
  • How to share accurate information about the virus
  • The challenge of vaccine hesitancy and declining immunization rates



Register for the webinar.


Virtual: Register for Immunize​.org Website Office Hours. Ask questions and learn about our "News & Updates" web section on June 11 at 4:00 p.m. (ET) or June 12 at 12:00 p.m. (ET). Recorded sessions available online.

To learn simple tips and tricks for using our website efficiently, please register for our next set of Website Office Hours on Wednesday, June 11 at 4:00 p.m. (ET) or Thursday, June 12 at 12:00 p.m. (ET). The same content will be covered in both sessions.

We will open each 45-minute session with a short, live demonstration on navigating our News & Updates website section. You can submit questions when you register or live on Zoom during the session.

Register today for Immunize​.org Website Office Hours (content is the same for both):

The archive of previous Website Office Hours content is posted at Immunize​.org’s "Webinars & Videos" page. These archived programs include Ask the Experts; Clinical Resources; Vaccine Information Statements (VISs); Images, Webinars, Videos, & Social Media; Official Guidance; Publication Archives, Vaccine Timeline, & About Us; Travel Vaccines, Vaccine Confidence, & Addressing Concerns; and Vaccines A–Z.

See our Calendar of Events for future Immunize​.org Website Office Hours.


For more upcoming events, visit our Calendar of Events.
Editorial Information

Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Gräbenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde
 
About IZ Express
Immunize​.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize​.org is the source of the material and provide a link to this issue.

IZ Express is supported in part by Grant No. NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize​.org and do not necessarily represent the official views of CDC.

IZ Express Disclaimer
ISSN: 2771-8085






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