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IZ Express #1,813: RSV infant hospitalization rates, live chikungunya vaccine use paused for age 60+, and more
| From | Immunize.org <[email protected]> |
| Subject | IZ Express #1,813: RSV infant hospitalization rates, live chikungunya vaccine use paused for age 60+, and more |
| Date | May 14, 2025 10:48 AM |
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Issue 1,813: May 14, 2025
Top Stories
* "Interim Evaluation of Respiratory Syncytial Virus Hospitalization Rates Among Infants and Young Children After Introduction of Respiratory Syncytial Virus Prevention Products — United States, October 2024–February 2025" published in MMWR
* FDA and CDC recommend pause in use of live chikungunya vaccine (Ixchiq, Valneva) in people age 60 years or older while safety reports are investigated
* Immunize.org updates references in two standing orders templates for hepatitis A vaccination
* Measles milestone: 1,001 confirmed measles cases reported in 30 states
* May is National Pet Month: Vaccination resources for household companions
* Learn how to find news content at Immunize.org on your smartphone in 3 minutes with our Orientation Video Series: “Introducing News and Updates Menu” (mobile view)
* Vaccines in the news
Immunize.org Website and Clinical Resources
* Spotlight on the website: Clinical Resources A–Z
Featured Resources
* Vaccinate adults! Order laminated 2025 U.S. adult immunization schedule booklets.
* Needle anxiety is common at any age. Use Immunize.org’s clinical resources to offer a positive vaccination experience.
* Immunize.org lifetime immunization record cards available for patient-held records
* Help Immunize.org reach more vaccinators through your social media networks. Follow us and share our posts on Facebook, Instagram, and LinkedIn!
Notable Publications
* Kaiser Family Foundation publishes poll results on vaccine safety and trust
Upcoming Events
* Virtual: CDC and AMA’s Project Firstline host webinar titled “Measles on the Rise: How to Prepare and Respond in Your Clinic” on May 15 at 11:00 a.m. (ET); CME credit available
* Virtual: University of Pennsylvania will present virtual seminar titled Decoding the Moment: "New Rules for Vaccine Approval" on May 16 at 2:00 p.m. (ET)
* Virtual: Register for Immunize.org Website Office Hours. Ask questions and learn about our "News & Updates" web section on June 11 at 4:00 p.m. (ET) or June 12 at 12:00 p.m. (ET). Recorded sessions available online.
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Top Stories
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"Interim Evaluation of Respiratory Syncytial Virus Hospitalization Rates Among Infants and Young Children After Introduction of Respiratory Syncytial Virus Prevention Products — United States, October 2024–February 2025" published in MMWR
CDC published Interim Evaluation of Respiratory Syncytial Virus Hospitalization Rates Among Infants and Young Children After Introduction of Respiratory Syncytial Virus Prevention Products—United States, October 2024–February 2025 ([link removed]) on May 8 in MMWR. A portion of the summary appears below.
Maternal respiratory syncytial virus (RSV) vaccine and nirsevimab, a long-acting monoclonal antibody, help prevent infant RSV-associated hospitalizations; these products became widely available in the United States during the 2024–25 RSV season. . . .
In this ecologic analysis comparing RSV-associated hospitalization rates among infants aged 0–7 months during 2024–25 with those during pre–COVID-19 pandemic RSV seasons in two surveillance networks, rates during 2024–25 were lower by an estimated 28% and 43%. . . .
In the first RSV season with widespread availability of maternal vaccine and nirsevimab, RSV-associated hospitalization rates among infants were lower than in prepandemic seasons. Effective health care planning is needed to protect infants as early in the RSV season as possible through maternal vaccination during pregnancy or infant receipt of nirsevimab.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]).
Related Links
* CDC: MMWR main page ([link removed]) providing access to the MMWR family of publications
* Immunize.org: Vaccines A–Z: RSV (Respiratory Syncytial Virus) ([link removed]) main page
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FDA and CDC recommend pause in use of live chikungunya vaccine (Ixchiq, Valneva) in people age 60 years or older while safety reports are investigated
On May 9, FDA and CDC recommended not administering the live chikungunya vaccine (CHIK-LA, Ixchiq, Valneva) to individuals age 60 years or older while an investigation of reported serious adverse events (SAEs) proceeds. The reported events include neurologic and cardiac events. This follows ACIP’s vote at its April 16 meeting to recommend adding a precaution to its use in people age 65 years and older after review of the preliminary safety data available at that time.
As of May 7, 17 serious adverse events, including two that resulted in death, have been reported in people age 62 through 89 years who received Ixchiq globally. Most of these reports involve people with underlying chronic medical conditions. Six cases were reported from the United States. Approximately 80,000 doses of Ixchiq have been distributed globally.
Ixchiq contains a live, weakened form of chikungunya virus and may cause symptoms like those of chikungunya disease. Some reports include events consistent with severe complications of chikungunya disease, resulting in hospitalization; one person died from encephalitis.
FDA will update its benefit-risk assessment for Ixchiq in people age 60 years or older. FDA and CDC will continue to evaluate safety reports for Ixchiq. During this assessment, FDA and CDC recommend a pause in use of Ixchiq in this age group. FDA and CDC will update the public when the agencies complete their evaluation.
A non-live, viral-like particle vaccine (CHIK-VLP, Vimkunya, Bavarian Nordic ([link removed]) ) was licensed by FDA for use in people age 12 years and older in February 2025. ACIP voted on recommendations for its use at its April 16 meeting; these ACIP recommendations will become official after being formally accepted by the CDC director (or by HHS leadership, in the absence of a CDC director). This has not yet occurred.
Related Links
* FDA: FDA and CDC Recommend Pause in Use of Ixchiq (Chikungunya Vaccine, Live) in Individuals 60 Years of Age and Older While Postmarketing Safety Reports are Investigated ([link removed]) (5/9/25)
* CDC Presentation to ACIP: Surveillance for Adverse Events Following Use of Live Attenuated Chikungunya Vaccine and its Use Among Travelers ([link removed]) (4/16/25)
* Immunize.org: Vaccines A–Z: Chikungunya ([link removed]) main page
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Immunize.org updates references in two standing orders templates for hepatitis A vaccination
Immunize.org updated the references on standing orders templates for infants, children, and adults to remove the reference to Appendix B ([link removed]) in the Epidemiology and Prevention of Vaccine-Preventable Diseases (the "Pink Book"). The updated standing order templates include:
* Standing Orders for Administering Hepatitis A Vaccine to Children and Teens ([link removed])
* Standing Orders for Administering Hepatitis A Vaccine to Adults ([link removed])
Related Links
* Immunize.org: Clinical Resources: Standing Orders Templates ([link removed]) main page
* Immunize.org: Clinical Resources A–Z ([link removed]) main page, where you can filter by topic, vaccine, language, or other criteria
* Immunize.org: Vaccines A–Z: Hepatitis A ([link removed]) main page
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Measles milestone: 1,001 confirmed measles cases reported in 30 states
As of May 8, CDC reported 1,001 confirmed measles cases ([link removed]) in 2025, with 93% of the cases associated with 14 outbreaks. North Dakota is the latest state to report confirmed cases. Most (709 of 1,001, 71%) were reported by the Texas Department of State Health Services ([link removed]). A map of 2025 confirmed measles cases, as of May 8, is shown below.
In response to growing measles outbreaks involving more than half of U.S. states, CDC published a suite of new resources for public health, healthcare professionals, and families in communities experiencing a measles outbreak. Resources include infographics for families, images to help clinic personnel identify cases, and a Be Ready for Measles communication toolkit ([link removed]) . A quick reference for healthcare professionals provides guidance for caring for patients with measles ([link removed]) . Find all these resources on the CDC Measles Cases and Outbreaks ([link removed]) page.
Related Links
* CDC: Measles Cases and Outbreaks ([link removed]) main page
* CDC: Be Ready for Measles Toolkit ([link removed])
* Immunize.org: Vaccines A–Z: Measles ([link removed]) main page
* Immunize.org: Standing Orders for Administering Measles, Mumps, and Rubella Vaccine to Children and Teens ([link removed]) (PDF)
* Immunize.org: Standing Orders for Administering Measles, Mumps, and Rubella Vaccine to Adults ([link removed]) (PDF)
* Immunize.org: Ask the Experts: MMR (Measles, Mumps, and Rubella) ([link removed]) web page
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May is National Pet Month: Vaccination resources for household companions
Vaccines are important for animal health. The resources below are helpful references for veterinary vaccination.
Related Links:
* American Animal Health Association (AAHA): Vaccination Resources ([link removed])
+ Canine Vaccination Guidelines ([link removed]) (2024), with infographic
+ Feline Vaccination Guidelines ([link removed]) (2020), with infographic
* American Veterinary Medical Association (AVMA): Vaccination ([link removed])
* American Society for the Prevention of Cruelty to Animals (ASPCA): Vaccinations for Your Pet ([link removed])
* Merck Veterinary Manual, open access, containing sections for:
+ Health professionals: Vaccines and Immunotherapy ([link removed])
+ Health professionals: Vaccination of Exotic Mammals ([link removed])
+ Owners: Pet Owners Overview ([link removed])
* National Association of State Public Health Veterinarians: NASPV Compendia ([link removed]) of guidelines
* U.S. Department of Agriculture (USDA), Animal & Plant Health Inspection Service (APHIS): Veterinary Biologics ([link removed])
+ List of Licensed Veterinary Biological Products ([link removed])
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Learn how to find news content at Immunize.org on your smartphone in 3 minutes with our Orientation Video Series: “Introducing News and Updates Menu” (mobile view)
Learn how to navigate Immunize.org’s news and updates section on the go with your smartphone. Check out the “mobile view” version of our 3-minute Orientation Video Series: Introducing News and Updates Menu ([link removed]).
See all the options in the Orientation Video Series ([link removed]) on our YouTube channel ([link removed]).
Share these videos with anyone who wants to learn more about effective immunization practices with Immunize.org.
* Immunize.org: Webinars & Videos; Orientation Video Series ([link removed]) page
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at ImmunizeOrg ([link removed])
* YouTube at ImmunizeOrg ([link removed])
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Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* Washington Post: Flu Killed 216 Children Nationwide this Season, the Highest Toll in Years ([link removed]) (5/8/25)
* Politico: States Loosen Vaccine Rules—Even as Measles Outbreak Rages ([link removed]) (5/7/25)
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Immunize.org Website and Clinical Resources
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Spotlight on the website: Clinical Resources A–Z
Immunize.org’s “Clinical Resources A–Z” section includes our printable resources that help two groups: patients and their families, as well as healthcare professionals.
To see this content, select “Clinical Resources A–Z,” the second main menu tab. From there, you can choose to view “All Patient Handouts,” “All Resources for Staff & Providers,” “Translations,” or a specific topic.
On the Search All Clinical Resources ([link removed]) page, narrow results either by entering keywords or by choosing one or more filters. Results are listed alphabetically by title and can also be sorted by item number or by date of most recent update. For a more compact display, you can hide document previews by toggling the “Hide/Show Images” button.
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Featured Resources
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Vaccinate adults! Order laminated 2025 U.S. adult immunization schedule booklets.
Laminated booklets of the 2025 U.S. adult immunization schedule ([link removed]) are still available in the Immunize.org shop. The 2025 child and adolescent schedule booklets sold out.
The schedules are available online as PDFs from CDC ([link removed]) at no cost. Immunize.org’s laminated booklets are ideal for use in any busy healthcare setting where vaccines are given. Features include:
* Durability: Their tough coating can be wiped down, and they can stand up to a year's worth of use.
* Format: Each schedule is produced in an 8.5” X 11” booklet format; with color coding for easy reading, our laminated schedules replicate the original CDC formatting, including all tables and notes. The adult schedule is 16 pages.
* Easy access to CDC updates: The CDC online schedule includes an addendum page that will display ACIP’s new recommendations as CDC adopts them during 2025. Each Immunize.org laminated schedule addendum page includes QR codes you can scan to view or print the online addendum page as it is revised.
* Bonus content: The schedule includes a bonus page with Immunize.org’s popular 1-page handout summarizing the dose, route, and needle size recommendations for all vaccines and recipients.
Pricing:
Adult Booklets
1 copy: $10.00
2–4 copies: $9.50 each
5–19 copies: $8.50 each
20–99 copies: $7.50 each
100–499 copies: $6.00 each
500–999 copies: $5.00 each
1,000–1,999 copies: $4.00 each
2,000+ copies: $3.25 each
Visit the Shop Immunize.org: Laminated Schedules ([link removed]) web page to view images and order today!
For additional information, call 651-647-9009 or email [email protected].
Related Links
* Immunize.org: Laminated Adult Immunization Schedules (19 and older) ([link removed]) web page
* Immunize.org: Shop Immunize.org ([link removed]) main page
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Needle anxiety is common at any age. Use Immunize.org’s clinical resources to offer a positive vaccination experience.
In Clinical Resources: Improving the Vaccination Experience ([link removed]), Immunize.org provides print and video tools to create a positive vaccination experience and ease injection anxiety in children and adults. Links to additional resources from trusted partner organizations are also provided.
The web page links to eight printable resources ([link removed]) on addressing vaccination anxiety (four for providers, four for recipients - also available in Spanish), two in-depth webinars, and six brief videos (listed below). As with all Immunize.org resources, these are free to download, link, copy, and share.
The video topics include:
* How to Administer Multiple Intramuscular Vaccines to Adults During One Visit ([link removed])
* Using Enhanced Screening Checklists for Contraindications to Vaccination ([link removed])
* Addressing Vaccination Anxiety for Infants: Strategies for Vaccine Recipients and Caregivers ([link removed])
* Addressing Vaccination Anxiety: Strategies for Healthcare Professionals ([link removed])
* Fainting Related to Vaccination: What You Need to Know ([link removed])
* Addressing Vaccination Anxiety for Children: Strategies for Vaccine Recipients and Caregivers ([link removed])
Related Link
* Immunize.org: Clinical Resources: Improving the Vaccination Experience ([link removed]) web page
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Immunize.org lifetime immunization record cards available for patient-held records
Immunize.org offers wallet-sized Lifetime Immunization Record Cards ([link removed]) , printed on rip-proof, smudge-proof, waterproof paper designed to last a lifetime. Sold in boxes of 250.
To purchase record cards, please visit the Immunize.org ([link removed]) ([link removed]) Shop ([link removed]).
Related Link
* Immunize.org: Shop Immunize.org ([link removed]) main page
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Help Immunize.org reach more vaccinators through your social media networks. Follow us and share our posts on Facebook, Instagram, and LinkedIn!
Immunize.org offers a social media program to highlight our educational resources for a new audience of vaccinators. Our social media channels feature our most popular printable resources and Ask the Experts questions, as well as announcements important to frontline vaccinators. Our short educational videos are all available on our YouTube channel in the Ask the Experts Video Series ([link removed]).
Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise:
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at Immunize.org ([link removed])
* YouTube at ImmunizeOrg ([link removed])
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Notable Publications
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Kaiser Family Foundation publishes poll results on vaccine safety and trust
According to the latest Tracking Poll on Health Information and Trust ([link removed]) conducted by the Kaiser Family Foundation (KFF) in April 2025, trust in government health agencies on vaccines shifted in ways that correlate with the respondents’ reported political affiliation.
Most adults say they are at least “somewhat confident” in the safety of many routine vaccines, including those for measles (83%), influenza (74%), and — among adults ages 50 and older for whom these vaccines are recommended — pneumococcal (82%) and shingles (79%).
Just over half (56%) of adults say they are at least “somewhat confident” that the COVID-19 vaccines are safe, including 89% of Democrats, 55% of independents, but just three in ten Republicans.
With the public split in their confidence of the safety of COVID-19 vaccines, the mRNA technology that many of these vaccines rely on remains little understood. About twice as many adults think vaccines that use mRNA technology are “generally safe” (32%) as say they are “generally unsafe” (16%), but about half (52%) report not knowing enough about this technology to say.
Nearly half of the public (45%) report having heard the false claim that mRNA vaccines can alter a person’s DNA – a myth related to COVID-19 vaccines that began circulating early in the pandemic.
[link removed]
Read the full report: KFF Tracking Poll on Health Information and Trust: Vaccine Safety and Trust ([link removed]) .
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Upcoming Events
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Virtual: CDC and AMA’s Project Firstline host webinar titled “Measles on the Rise: How to Prepare and Respond in Your Clinic” on May 15 at 11:00 a.m. (ET); CME credit available
CDC and the American Medical Association (AMA) will present a 1-hour webinar titled Measles on the Rise: How to Prepare and Respond in Your Clinic ([link removed]) beginning at 11:00 a.m. (ET) on May 15. Part of Project Firstline ([link removed]), CDC's national training collaborative for infection prevention and control, experts from CDC and AMA will share current trends in measles epidemiology, clinical recognition, the importance of vaccination, and how to prepare for and respond to measles.
Free continuing-education credits (CME) will be available.
Register for the webinar ([link removed]).
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Virtual: University of Pennsylvania will present virtual seminar titled Decoding the Moment: "New Rules for Vaccine Approval" on May 16 at 2:00 p.m. (ET)
The University of Pennsylvania will present a 45-minute virtual seminar produced by the media company, Tradeoffs, entitled Decoding the Moment: New Rules for Vaccine Approval ([link removed]) beginning at 2:00 p.m. (ET) on May 16. Part of its Decoding the Moment series, the conversation will feature Paul Offit, MD, director of the Vaccine Education Center (VEC) at the Children's Hospital of Philadelphia (CHOP). The discussion will tackle the recent proposal that all “new” vaccines be tested against a placebo, and what it could mean for vaccine availability, public confidence, and disease transmission.
Register for the event ([link removed]).
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Virtual: Register for Immunize.org Website Office Hours. Ask questions and learn about our "News & Updates" web section on June 11 at 4:00 p.m. (ET) or June 12 at 12:00 p.m. (ET). Recorded sessions available online.
To learn simple tips and tricks for using our website efficiently, please register for our next set of Website Office Hours on Wednesday, June 11 at 4:00 p.m. (ET) ([link removed]) or Thursday, June 12 at 12:00 p.m. (ET) ([link removed]). The same content will be covered in both sessions.
We will open each 45-minute session with a short, live demonstration on navigating ourNews & Updates ([link removed]) website section. You can submit questions when you register or live on Zoom during the session.
Register today for Immunize.org Website Office Hours (content is the same for both):
* Wednesday, June 11 at 4:00 p.m. (ET) ([link removed])
* Thursday, June 12 at 12:00 p.m. (ET) ([link removed])
The archive of previous Website Office Hours content is posted at Immunize.org’s Webinars & Videos ([link removed]) page. These archived programs include Ask the Experts; Clinical Resources; Vaccine Information Statements (VISs); Images, Webinars, Videos, & Social Media; Official Guidance; Publication Archives, Vaccine Timeline, & About Us; Travel Vaccines, Vaccine Confidence, & Addressing Concerns; and Vaccines A–Z.
Mark your calendar ([link removed]) for future Immunize.org Website Office Hours.
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For more upcoming events, visit our Calendar of Events ([link removed]).
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Gräbenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]).
IZ Express is supported in part by Grant No. NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
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Issue 1,813: May 14, 2025
Top Stories
* "Interim Evaluation of Respiratory Syncytial Virus Hospitalization Rates Among Infants and Young Children After Introduction of Respiratory Syncytial Virus Prevention Products — United States, October 2024–February 2025" published in MMWR
* FDA and CDC recommend pause in use of live chikungunya vaccine (Ixchiq, Valneva) in people age 60 years or older while safety reports are investigated
* Immunize.org updates references in two standing orders templates for hepatitis A vaccination
* Measles milestone: 1,001 confirmed measles cases reported in 30 states
* May is National Pet Month: Vaccination resources for household companions
* Learn how to find news content at Immunize.org on your smartphone in 3 minutes with our Orientation Video Series: “Introducing News and Updates Menu” (mobile view)
* Vaccines in the news
Immunize.org Website and Clinical Resources
* Spotlight on the website: Clinical Resources A–Z
Featured Resources
* Vaccinate adults! Order laminated 2025 U.S. adult immunization schedule booklets.
* Needle anxiety is common at any age. Use Immunize.org’s clinical resources to offer a positive vaccination experience.
* Immunize.org lifetime immunization record cards available for patient-held records
* Help Immunize.org reach more vaccinators through your social media networks. Follow us and share our posts on Facebook, Instagram, and LinkedIn!
Notable Publications
* Kaiser Family Foundation publishes poll results on vaccine safety and trust
Upcoming Events
* Virtual: CDC and AMA’s Project Firstline host webinar titled “Measles on the Rise: How to Prepare and Respond in Your Clinic” on May 15 at 11:00 a.m. (ET); CME credit available
* Virtual: University of Pennsylvania will present virtual seminar titled Decoding the Moment: "New Rules for Vaccine Approval" on May 16 at 2:00 p.m. (ET)
* Virtual: Register for Immunize.org Website Office Hours. Ask questions and learn about our "News & Updates" web section on June 11 at 4:00 p.m. (ET) or June 12 at 12:00 p.m. (ET). Recorded sessions available online.
------------------------------------------------------------
Top Stories
------------------------------------------------------------
"Interim Evaluation of Respiratory Syncytial Virus Hospitalization Rates Among Infants and Young Children After Introduction of Respiratory Syncytial Virus Prevention Products — United States, October 2024–February 2025" published in MMWR
CDC published Interim Evaluation of Respiratory Syncytial Virus Hospitalization Rates Among Infants and Young Children After Introduction of Respiratory Syncytial Virus Prevention Products—United States, October 2024–February 2025 ([link removed]) on May 8 in MMWR. A portion of the summary appears below.
Maternal respiratory syncytial virus (RSV) vaccine and nirsevimab, a long-acting monoclonal antibody, help prevent infant RSV-associated hospitalizations; these products became widely available in the United States during the 2024–25 RSV season. . . .
In this ecologic analysis comparing RSV-associated hospitalization rates among infants aged 0–7 months during 2024–25 with those during pre–COVID-19 pandemic RSV seasons in two surveillance networks, rates during 2024–25 were lower by an estimated 28% and 43%. . . .
In the first RSV season with widespread availability of maternal vaccine and nirsevimab, RSV-associated hospitalization rates among infants were lower than in prepandemic seasons. Effective health care planning is needed to protect infants as early in the RSV season as possible through maternal vaccination during pregnancy or infant receipt of nirsevimab.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]).
Related Links
* CDC: MMWR main page ([link removed]) providing access to the MMWR family of publications
* Immunize.org: Vaccines A–Z: RSV (Respiratory Syncytial Virus) ([link removed]) main page
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FDA and CDC recommend pause in use of live chikungunya vaccine (Ixchiq, Valneva) in people age 60 years or older while safety reports are investigated
On May 9, FDA and CDC recommended not administering the live chikungunya vaccine (CHIK-LA, Ixchiq, Valneva) to individuals age 60 years or older while an investigation of reported serious adverse events (SAEs) proceeds. The reported events include neurologic and cardiac events. This follows ACIP’s vote at its April 16 meeting to recommend adding a precaution to its use in people age 65 years and older after review of the preliminary safety data available at that time.
As of May 7, 17 serious adverse events, including two that resulted in death, have been reported in people age 62 through 89 years who received Ixchiq globally. Most of these reports involve people with underlying chronic medical conditions. Six cases were reported from the United States. Approximately 80,000 doses of Ixchiq have been distributed globally.
Ixchiq contains a live, weakened form of chikungunya virus and may cause symptoms like those of chikungunya disease. Some reports include events consistent with severe complications of chikungunya disease, resulting in hospitalization; one person died from encephalitis.
FDA will update its benefit-risk assessment for Ixchiq in people age 60 years or older. FDA and CDC will continue to evaluate safety reports for Ixchiq. During this assessment, FDA and CDC recommend a pause in use of Ixchiq in this age group. FDA and CDC will update the public when the agencies complete their evaluation.
A non-live, viral-like particle vaccine (CHIK-VLP, Vimkunya, Bavarian Nordic ([link removed]) ) was licensed by FDA for use in people age 12 years and older in February 2025. ACIP voted on recommendations for its use at its April 16 meeting; these ACIP recommendations will become official after being formally accepted by the CDC director (or by HHS leadership, in the absence of a CDC director). This has not yet occurred.
Related Links
* FDA: FDA and CDC Recommend Pause in Use of Ixchiq (Chikungunya Vaccine, Live) in Individuals 60 Years of Age and Older While Postmarketing Safety Reports are Investigated ([link removed]) (5/9/25)
* CDC Presentation to ACIP: Surveillance for Adverse Events Following Use of Live Attenuated Chikungunya Vaccine and its Use Among Travelers ([link removed]) (4/16/25)
* Immunize.org: Vaccines A–Z: Chikungunya ([link removed]) main page
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Immunize.org updates references in two standing orders templates for hepatitis A vaccination
Immunize.org updated the references on standing orders templates for infants, children, and adults to remove the reference to Appendix B ([link removed]) in the Epidemiology and Prevention of Vaccine-Preventable Diseases (the "Pink Book"). The updated standing order templates include:
* Standing Orders for Administering Hepatitis A Vaccine to Children and Teens ([link removed])
* Standing Orders for Administering Hepatitis A Vaccine to Adults ([link removed])
Related Links
* Immunize.org: Clinical Resources: Standing Orders Templates ([link removed]) main page
* Immunize.org: Clinical Resources A–Z ([link removed]) main page, where you can filter by topic, vaccine, language, or other criteria
* Immunize.org: Vaccines A–Z: Hepatitis A ([link removed]) main page
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Measles milestone: 1,001 confirmed measles cases reported in 30 states
As of May 8, CDC reported 1,001 confirmed measles cases ([link removed]) in 2025, with 93% of the cases associated with 14 outbreaks. North Dakota is the latest state to report confirmed cases. Most (709 of 1,001, 71%) were reported by the Texas Department of State Health Services ([link removed]). A map of 2025 confirmed measles cases, as of May 8, is shown below.
In response to growing measles outbreaks involving more than half of U.S. states, CDC published a suite of new resources for public health, healthcare professionals, and families in communities experiencing a measles outbreak. Resources include infographics for families, images to help clinic personnel identify cases, and a Be Ready for Measles communication toolkit ([link removed]) . A quick reference for healthcare professionals provides guidance for caring for patients with measles ([link removed]) . Find all these resources on the CDC Measles Cases and Outbreaks ([link removed]) page.
Related Links
* CDC: Measles Cases and Outbreaks ([link removed]) main page
* CDC: Be Ready for Measles Toolkit ([link removed])
* Immunize.org: Vaccines A–Z: Measles ([link removed]) main page
* Immunize.org: Standing Orders for Administering Measles, Mumps, and Rubella Vaccine to Children and Teens ([link removed]) (PDF)
* Immunize.org: Standing Orders for Administering Measles, Mumps, and Rubella Vaccine to Adults ([link removed]) (PDF)
* Immunize.org: Ask the Experts: MMR (Measles, Mumps, and Rubella) ([link removed]) web page
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May is National Pet Month: Vaccination resources for household companions
Vaccines are important for animal health. The resources below are helpful references for veterinary vaccination.
Related Links:
* American Animal Health Association (AAHA): Vaccination Resources ([link removed])
+ Canine Vaccination Guidelines ([link removed]) (2024), with infographic
+ Feline Vaccination Guidelines ([link removed]) (2020), with infographic
* American Veterinary Medical Association (AVMA): Vaccination ([link removed])
* American Society for the Prevention of Cruelty to Animals (ASPCA): Vaccinations for Your Pet ([link removed])
* Merck Veterinary Manual, open access, containing sections for:
+ Health professionals: Vaccines and Immunotherapy ([link removed])
+ Health professionals: Vaccination of Exotic Mammals ([link removed])
+ Owners: Pet Owners Overview ([link removed])
* National Association of State Public Health Veterinarians: NASPV Compendia ([link removed]) of guidelines
* U.S. Department of Agriculture (USDA), Animal & Plant Health Inspection Service (APHIS): Veterinary Biologics ([link removed])
+ List of Licensed Veterinary Biological Products ([link removed])
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Learn how to find news content at Immunize.org on your smartphone in 3 minutes with our Orientation Video Series: “Introducing News and Updates Menu” (mobile view)
Learn how to navigate Immunize.org’s news and updates section on the go with your smartphone. Check out the “mobile view” version of our 3-minute Orientation Video Series: Introducing News and Updates Menu ([link removed]).
See all the options in the Orientation Video Series ([link removed]) on our YouTube channel ([link removed]).
Share these videos with anyone who wants to learn more about effective immunization practices with Immunize.org.
* Immunize.org: Webinars & Videos; Orientation Video Series ([link removed]) page
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at ImmunizeOrg ([link removed])
* YouTube at ImmunizeOrg ([link removed])
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Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* Washington Post: Flu Killed 216 Children Nationwide this Season, the Highest Toll in Years ([link removed]) (5/8/25)
* Politico: States Loosen Vaccine Rules—Even as Measles Outbreak Rages ([link removed]) (5/7/25)
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Immunize.org Website and Clinical Resources
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Spotlight on the website: Clinical Resources A–Z
Immunize.org’s “Clinical Resources A–Z” section includes our printable resources that help two groups: patients and their families, as well as healthcare professionals.
To see this content, select “Clinical Resources A–Z,” the second main menu tab. From there, you can choose to view “All Patient Handouts,” “All Resources for Staff & Providers,” “Translations,” or a specific topic.
On the Search All Clinical Resources ([link removed]) page, narrow results either by entering keywords or by choosing one or more filters. Results are listed alphabetically by title and can also be sorted by item number or by date of most recent update. For a more compact display, you can hide document previews by toggling the “Hide/Show Images” button.
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Featured Resources
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Vaccinate adults! Order laminated 2025 U.S. adult immunization schedule booklets.
Laminated booklets of the 2025 U.S. adult immunization schedule ([link removed]) are still available in the Immunize.org shop. The 2025 child and adolescent schedule booklets sold out.
The schedules are available online as PDFs from CDC ([link removed]) at no cost. Immunize.org’s laminated booklets are ideal for use in any busy healthcare setting where vaccines are given. Features include:
* Durability: Their tough coating can be wiped down, and they can stand up to a year's worth of use.
* Format: Each schedule is produced in an 8.5” X 11” booklet format; with color coding for easy reading, our laminated schedules replicate the original CDC formatting, including all tables and notes. The adult schedule is 16 pages.
* Easy access to CDC updates: The CDC online schedule includes an addendum page that will display ACIP’s new recommendations as CDC adopts them during 2025. Each Immunize.org laminated schedule addendum page includes QR codes you can scan to view or print the online addendum page as it is revised.
* Bonus content: The schedule includes a bonus page with Immunize.org’s popular 1-page handout summarizing the dose, route, and needle size recommendations for all vaccines and recipients.
Pricing:
Adult Booklets
1 copy: $10.00
2–4 copies: $9.50 each
5–19 copies: $8.50 each
20–99 copies: $7.50 each
100–499 copies: $6.00 each
500–999 copies: $5.00 each
1,000–1,999 copies: $4.00 each
2,000+ copies: $3.25 each
Visit the Shop Immunize.org: Laminated Schedules ([link removed]) web page to view images and order today!
For additional information, call 651-647-9009 or email [email protected].
Related Links
* Immunize.org: Laminated Adult Immunization Schedules (19 and older) ([link removed]) web page
* Immunize.org: Shop Immunize.org ([link removed]) main page
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Needle anxiety is common at any age. Use Immunize.org’s clinical resources to offer a positive vaccination experience.
In Clinical Resources: Improving the Vaccination Experience ([link removed]), Immunize.org provides print and video tools to create a positive vaccination experience and ease injection anxiety in children and adults. Links to additional resources from trusted partner organizations are also provided.
The web page links to eight printable resources ([link removed]) on addressing vaccination anxiety (four for providers, four for recipients - also available in Spanish), two in-depth webinars, and six brief videos (listed below). As with all Immunize.org resources, these are free to download, link, copy, and share.
The video topics include:
* How to Administer Multiple Intramuscular Vaccines to Adults During One Visit ([link removed])
* Using Enhanced Screening Checklists for Contraindications to Vaccination ([link removed])
* Addressing Vaccination Anxiety for Infants: Strategies for Vaccine Recipients and Caregivers ([link removed])
* Addressing Vaccination Anxiety: Strategies for Healthcare Professionals ([link removed])
* Fainting Related to Vaccination: What You Need to Know ([link removed])
* Addressing Vaccination Anxiety for Children: Strategies for Vaccine Recipients and Caregivers ([link removed])
Related Link
* Immunize.org: Clinical Resources: Improving the Vaccination Experience ([link removed]) web page
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Immunize.org lifetime immunization record cards available for patient-held records
Immunize.org offers wallet-sized Lifetime Immunization Record Cards ([link removed]) , printed on rip-proof, smudge-proof, waterproof paper designed to last a lifetime. Sold in boxes of 250.
To purchase record cards, please visit the Immunize.org ([link removed]) ([link removed]) Shop ([link removed]).
Related Link
* Immunize.org: Shop Immunize.org ([link removed]) main page
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Help Immunize.org reach more vaccinators through your social media networks. Follow us and share our posts on Facebook, Instagram, and LinkedIn!
Immunize.org offers a social media program to highlight our educational resources for a new audience of vaccinators. Our social media channels feature our most popular printable resources and Ask the Experts questions, as well as announcements important to frontline vaccinators. Our short educational videos are all available on our YouTube channel in the Ask the Experts Video Series ([link removed]).
Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise:
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at Immunize.org ([link removed])
* YouTube at ImmunizeOrg ([link removed])
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Notable Publications
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Kaiser Family Foundation publishes poll results on vaccine safety and trust
According to the latest Tracking Poll on Health Information and Trust ([link removed]) conducted by the Kaiser Family Foundation (KFF) in April 2025, trust in government health agencies on vaccines shifted in ways that correlate with the respondents’ reported political affiliation.
Most adults say they are at least “somewhat confident” in the safety of many routine vaccines, including those for measles (83%), influenza (74%), and — among adults ages 50 and older for whom these vaccines are recommended — pneumococcal (82%) and shingles (79%).
Just over half (56%) of adults say they are at least “somewhat confident” that the COVID-19 vaccines are safe, including 89% of Democrats, 55% of independents, but just three in ten Republicans.
With the public split in their confidence of the safety of COVID-19 vaccines, the mRNA technology that many of these vaccines rely on remains little understood. About twice as many adults think vaccines that use mRNA technology are “generally safe” (32%) as say they are “generally unsafe” (16%), but about half (52%) report not knowing enough about this technology to say.
Nearly half of the public (45%) report having heard the false claim that mRNA vaccines can alter a person’s DNA – a myth related to COVID-19 vaccines that began circulating early in the pandemic.
[link removed]
Read the full report: KFF Tracking Poll on Health Information and Trust: Vaccine Safety and Trust ([link removed]) .
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Upcoming Events
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Virtual: CDC and AMA’s Project Firstline host webinar titled “Measles on the Rise: How to Prepare and Respond in Your Clinic” on May 15 at 11:00 a.m. (ET); CME credit available
CDC and the American Medical Association (AMA) will present a 1-hour webinar titled Measles on the Rise: How to Prepare and Respond in Your Clinic ([link removed]) beginning at 11:00 a.m. (ET) on May 15. Part of Project Firstline ([link removed]), CDC's national training collaborative for infection prevention and control, experts from CDC and AMA will share current trends in measles epidemiology, clinical recognition, the importance of vaccination, and how to prepare for and respond to measles.
Free continuing-education credits (CME) will be available.
Register for the webinar ([link removed]).
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Virtual: University of Pennsylvania will present virtual seminar titled Decoding the Moment: "New Rules for Vaccine Approval" on May 16 at 2:00 p.m. (ET)
The University of Pennsylvania will present a 45-minute virtual seminar produced by the media company, Tradeoffs, entitled Decoding the Moment: New Rules for Vaccine Approval ([link removed]) beginning at 2:00 p.m. (ET) on May 16. Part of its Decoding the Moment series, the conversation will feature Paul Offit, MD, director of the Vaccine Education Center (VEC) at the Children's Hospital of Philadelphia (CHOP). The discussion will tackle the recent proposal that all “new” vaccines be tested against a placebo, and what it could mean for vaccine availability, public confidence, and disease transmission.
Register for the event ([link removed]).
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Virtual: Register for Immunize.org Website Office Hours. Ask questions and learn about our "News & Updates" web section on June 11 at 4:00 p.m. (ET) or June 12 at 12:00 p.m. (ET). Recorded sessions available online.
To learn simple tips and tricks for using our website efficiently, please register for our next set of Website Office Hours on Wednesday, June 11 at 4:00 p.m. (ET) ([link removed]) or Thursday, June 12 at 12:00 p.m. (ET) ([link removed]). The same content will be covered in both sessions.
We will open each 45-minute session with a short, live demonstration on navigating ourNews & Updates ([link removed]) website section. You can submit questions when you register or live on Zoom during the session.
Register today for Immunize.org Website Office Hours (content is the same for both):
* Wednesday, June 11 at 4:00 p.m. (ET) ([link removed])
* Thursday, June 12 at 12:00 p.m. (ET) ([link removed])
The archive of previous Website Office Hours content is posted at Immunize.org’s Webinars & Videos ([link removed]) page. These archived programs include Ask the Experts; Clinical Resources; Vaccine Information Statements (VISs); Images, Webinars, Videos, & Social Media; Official Guidance; Publication Archives, Vaccine Timeline, & About Us; Travel Vaccines, Vaccine Confidence, & Addressing Concerns; and Vaccines A–Z.
Mark your calendar ([link removed]) for future Immunize.org Website Office Hours.
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For more upcoming events, visit our Calendar of Events ([link removed]).
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Gräbenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]).
IZ Express is supported in part by Grant No. NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
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