From TradeBriefs <[email protected]>
Subject Could psychedelics be fine-tuned to relieve anxiety but skip the 'trip'? - Feb 19, 2025
Date February 19, 2025 2:21 PM
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- The top 25 stories curated by editors and fellow readers!

Editor's Pick

Life expectancy growth stalls across Europe as England sees sharpest
decline, say researchers

[[link removed]}&lead=419599&emailid=146606&nl=daily diet,
obesity and inactivity blamed on decline with Norway the only country
seeing a rise

Continued here
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Editor's Note: "The slowdown in life expectancy improvements,
particularly due to cardiovascular disease and cancer, highlights the
urgent need for stronger action on the root causes - poor diet,
physical inactivity, and obesity."

Work

Could psychedelics be fine-tuned to relieve anxiety but skip the
'trip'? [[link removed]}&lead=419599&emailid=146606&nl=daily]
[[link removed]}&lead=419599&emailid=146606&nl=daily]
Anxiety disorders are serious and debilitating, but undertreated.

Work

Gaba is the off switch of the brain: Is it also the answer to better
sleep, sobriety and less anxiety?
[[link removed]}&lead=419599&emailid=146606&nl=daily]
[[link removed]}&lead=419599&emailid=146606&nl=daily]
"Chinese medicine." "That weird Hungarian liqueur." "Something my
grandad would drink." The taste test is not going well. Dry January is
over and we're hitting the bottle, but this is not alcohol we're
drinking.















Work

Japan backs nuclear power in climate plan criticized as insufficient
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The government approved separate plans Tuesday to reduce greenhouse
gas emissions by 60% in the fiscal year from April 2035 -- and by 73%
in fiscal 2040 -- compared with 2013 levels, and have renewables and
nuclear power generate half and 20% of the country's electricity,
respectively, by 2040.

Work

The dietary supplements you think are improving your health may be
damaging your liver, research warns
[[link removed]}&lead=419599&emailid=146606&nl=daily]
BYHerbal and dietary supplements account for roughly 20% of liver
toxicity cases nationwide, according to 2017 research published in the
journal Hepatology.














Work

Why enterprises are turning to small AI models
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Large language models are all the rage, but small language models have
gained traction and business use is set to rise this year, according
to analysts.

Work

HP is buying Humane and shutting down the AI Pin
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[[link removed]}&lead=419599&emailid=146606&nl=daily]
Humane is selling "key AI capabilities" to HP for $116 million and
will stop selling AI Pin, the company announced today. AI Pins that
have already been purchased will continue to function normally until
3PM ET on February 28th, Humane says in a support document.














Work

Skibidi Toilet studio looking to flush out imitators in court
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Have the words "Skidibi Toilet" ever been uttered in court? That's
unlikely -- and changing soon.

Work

China Looks to Use Tesla FSD Rollout as Leverage in Trade Negotiations
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There has been a lot of speculation over how Elon Musk's close
involvement in the new Trump administration could affect the fortunes
of his vast business empire. On the one hand, President Trump could
ease the regulatory environment on Tesla, and hand even more
government contracts to SpaceX.














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Net-zero homes are touted as a solution for climate change, but they
remain out of reach for most
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Net-zero homes use natural energy sources and are designed to use less
energy and, as such, are considered important in the fight against
climate change. But for the average Canadian, they're still out of
reach. Net-zero homes are important for tackling climate change.

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Out-analyzing analysts: OpenAI's Deep Research pairs reasoning LLMs
with agentic RAG to automate work -- and replace jobs
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Join our daily and weekly newsletters for the latest updates and
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Toyota steps in to support Michigan EV battery plant with $1.5B order
after GM backs out
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In a turn of events, Toyota is stepping in to support LG Energy
Solution's EV battery plant in Michigan. Toyota reportedly placed a
$1.5 billion order to boost operations at the facility after GM backed
out.

Work

AK47 attack on Brazil mayor was setup to boost reelection bid, police
claim
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As campaign strategies go it was unorthodox and illegal: buy an AK-47,
hire a pair of phony hitmen, and stage a fake assassination attempt
against the mayor that would generate public sympathy and help him win
a second term in power.














Work

Pancreatic cancer: blocked nerves as a possible new treatment strategy
[[link removed]}&lead=419599&emailid=146606&nl=daily]
For several years, scientists have been discovering interactions with
the nervous system in almost all types of cancer studied, interactions
that in many cases promote tumor growth and survival. This also
applies to pancreatic cancer, which is interwoven with a dense network
of nerves.

Work

Children are starting school unable to sit up or hold a pencil and I
know the culprit
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[[link removed]}&lead=419599&emailid=146606&nl=daily]
As an early years education specialist, over the past decade I have
seen children enter classrooms with fewer and fewer of the skills
needed to begin their formal education. The key culprit, in my
opinion? Screen time. On a child's first day at school, it's normal to
expect a few nerves.














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Shuhei Yoshida Was Allegedly Forced Out of PlayStation Studios Job by
Jim Ryan
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[[link removed]}&lead=419599&emailid=146606&nl=daily]
Popular former PlayStation executive Shuhei Yoshida has claimed that
he was forced to step down from his PlayStation Studios role by then
CEO Jim Ryan.

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Bioengineers Reveal Key to Reversing Cellular Aging
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The key to reversing cellular aging may lie in a protein responsible
for toggling cells between a "young" and an "old" state. This is the
conclusion of researchers from the University of Osaka, who
experimented with the expression of the protein "AP2A1" in cells of
different ages.













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The Ketamine-Fueled 'Psychedelic Slumber Parties' That Get Tech Execs
Back on Track
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"Ketamine is helpful for getting one out of the negative frame of
mind," Elon Musk told an interviewer last year. The unelected man
currently gutting US federal programs isn't the only one who thinks
so.

Work

The revolt of the 'low performers'
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[[link removed]}&lead=419599&emailid=146606&nl=daily]
Mark Zuckerberg dissed their work. Now they're fighting back on
LinkedIn. At this point, it's become so common it's a social media
cliche: the post-layoff note on LinkedIn.

Work

There's a tiny chance the asteroid headed for Earth could hit the moon
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[[link removed]}&lead=419599&emailid=146606&nl=daily]
Asteroid 2024 YR4 is on a potential crash course with Earth, but
there's a very slight chance the moon could take the hit. Based on
current observations, there is a 2.

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The Four Quadrants of Conformism
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One of the most revealing ways to classify people is by the degree and
aggressiveness of their conformism.

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Understanding the Mechanisms : A Comprehensive Analysis of Dr. Rhonda
Patrick's Insights on Vigorous Exercise and its Impact on Longevity
and Brain Health
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[[link removed]}&lead=419599&emailid=146606&nl=daily]
A recent podcast by Dr. Rhonda Patrick, titled "The Longevity & Brain
Benefits of Vigorous Exercise", has shed light on the numerous
advantages of high-intensity vigorous exercise. Dr.

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Wikipedia's Co-Founder Is Wikipedia's Most Outspoken Critic
[[link removed]}&lead=419599&emailid=146606&nl=daily]
In Slubice, Poland, there's a monument to Wikipedia, the inscription
on which reads: "Wikipedia [is] the greatest project co-created by
people regardless of political, religious, or cultural borders.

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How to Get PFAS Out of Drinking Water--and Keep It Out
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[[link removed]}&lead=419599&emailid=146606&nl=daily]
Filters in water pitchers or under-sink systems capture dangerous
chemicals, only for them to be returned to the environment. A
researcher from North Carolina is pioneering a new system that could
get rid of forever chemicals forever.

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The Teeming Life of Dead Trees
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Rotting logs turn out to be vital to forest biodiversity and recycling
organic matter.

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A Mathematician Who Makes the Best of Things
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[[link removed]}&lead=419599&emailid=146606&nl=daily]
The words "optimal" and "optimize" derive from the Latin "optimus," or
"best," as in "make the best of things." Alessio Figalli, a
mathematician at the university ETH Zurich, studies optimal transport:
the most efficient allocation of starting points to end points.

Work

CAR T-cells enable record-breaking 18-year nerve cancer remission
[[link removed]}&lead=419599&emailid=146606&nl=daily]
[[link removed]}&lead=419599&emailid=146606&nl=daily]
A cancer therapy that uses genetically engineered immune cells, called
CAR T-cells, has kept a person free of a potentially fatal nerve
tumour for a record-breaking 18 years.

Work

On the ground with Ukraine's volunteer drone hunters
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Located on the banks of the Dnipro river, about 90 kilometres south
east of Kyiv, the small town of Pereiaslav is situated squarely in the
flight path for Russia's near-nightly drone and missile attacks that
target the Ukrainian capital.

Work

The Future Is Solo: AI Is Creating Billion-Dollar One-Person Companies
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Nostalgia is the best word to describe Emily's feelings as she sits
beside her colleagues at a conference table in a sleek high-rise
building.

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Argentine presidents promotion of crypto rocks his presidency - WSJ
(No paywall) [[link removed]}&lead=419599&emailid=146606&nl=daily]
[[link removed]}&lead=419599&emailid=146606&nl=daily]
Argentine President Javier Milei has been on the defensive after a
cryptocurrency he endorsed on X saw its value crash, triggering fraud
allegations and calls for impeachment by his political foes.

Work

Trump floats 25% tariffs on autos, chips, pharmaceuticals - WSJ (No
paywall) [[link removed]}&lead=419599&emailid=146606&nl=daily]
[[link removed]}&lead=419599&emailid=146606&nl=daily]
The tariffs on those industries may increase over time, Trump told
reporters gathered at his Mar-a-Lago club in Florida, though he added
that companies may be given a phase-in period to move production back
to the U.S.

Work

The battle for overhead bins is raging. These are the rules to play
by. - WSJ (No paywall) [[link removed]}&lead=419599&emailid=146606&nl=daily]
[[link removed]}&lead=419599&emailid=146606&nl=daily]
You know, the travelers who stuff everything they lugged onto the
plane into the overhead bin as if they own it. Or the people who go
all Tetris" on your stuff to squeeze their bag in. And lets not forget
the passengers who willfully ignore the reserved signs and plop their
bags in the first-class or economy-plus bins.

Work

Should Google Stay in the Cloud Gaming Business? - Harvard Business
Review (No paywall) [[link removed]}&lead=419599&emailid=146606&nl=daily]
[[link removed]}&lead=419599&emailid=146606&nl=daily]
Google formally announced the innovative video game service Stadia at
the 2019 Game Developer Conference. The company invested substantial
resources and time into building a network able to support the
demanding requirements of cloud gaming. But the early uptake by
premium video gamers was disappointing.

Work

Trump signs order to expand IVF by making it more affordable - STAT
(No paywall) [[link removed]}&lead=419599&emailid=146606&nl=daily]
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The order calls for policy recommendations to protect IVF access and
aggressively reduce out-of-pocket and health plan costs for such
treatments, according to the White House. On the campaign trail,
Trumpcalled for universal coverage of IVFtreatment after his Supreme
Court nominees helped to overturn Roe v. Wade, leading to a wave of
restrictions in Republican-led states, including some that have
threatened access to IVF by trying to define life as beginning at
conception.

Work

Ex-Brazil President Bolsonaro Charged With Overseeing Alleged Coup
Plot That Included Plan To Poison Successor Lula - Forbes (No paywall)
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Brazilian authorities on Tuesday charged Jair Bolsonaro, the countrys
former president, for his role in allegedly plotting a coup to
overturn his loss in the countrys 2022 presidential electionswhich
included a purported plan to poison his rival and successor President
Lula da Silva.

Work

KKR confronts 449mn earnings hole as flagship Italian deal sours - FT
(No paywall) [[link removed]}&lead=419599&emailid=146606&nl=daily]
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Private equity group clashed with management over diverging forecasts
for telecoms business

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U.S., Russia Meet in Riyadh to Discuss UkraineWithout Inviting Kyiv -
Foreign Policy (No paywall) [[link removed]}&lead=419599&emailid=146606&nl=daily]
[[link removed]}&lead=419599&emailid=146606&nl=daily]
World Brief: U.S., Russia Meet in Riyadh to Discuss UkraineWithout
Inviting Kyiv

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Trump Floats 25% Tariffs on US Auto, Drug, Chip Imports - Bloomberg
(No paywall) [[link removed]}&lead=419599&emailid=146606&nl=daily]
[[link removed]}&lead=419599&emailid=146606&nl=daily]
New duties would widen trade war, hit key consumer products Trump has
proposed reciprocal tariffs, duties on metals

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Robert F. Kennedy Jr. reverses course on childhood vaccine schedule
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Anna Commander is a Newsweek Editor and writer based in Florida. Her
focus is reporting on crime, weather and breaking news. She has
covered weather, and major breaking news events in South Florida. Anna
joined Newsweek in 2022 from The National Desk in Washington, D.C. and
had previously worked at CBS12 News in West Palm Beach. She is a
graduate of Florida Atlantic University. You can get in touch with
Anna by emailing [email protected].

Work

Social Media Fails Many Users. Experts Have an Idea to Fix It
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Social medias shortfalls are becoming more evident than ever. Most
platforms have been designed to maximize user engagement as a means of
generating advertising revenuea model that exploits our worst
impulses, rewarding sensational and provocative content while creating
division and polarization, and leaving many feeling anxious and
isolated in the process.

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Germanys economy is driving off a cliff. The car industry is behind
the wheel.
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Automakers are facing a perfect storm: a shift from the combustion
engine, which showcased German engineering, to less complex electric
vehicles where Germany doesnt control crucial battery technology. They
are also battling slumping demand for electric vehicles in Europe,
high energy and labor costs, a collapse of sales in their key market
of China, and the arrival of aggressive Chinese rivals on the
continent.

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Japan adopts new carbon reduction targets as it plans to boost nuclear
and renewable energy by 2040
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TOKYO (AP) -- Japan's government adopted on Tuesday new
decarbonization targets aiming to reduce greenhouse gas emissions by
more than 70% from 2013 levels over the next 15 years, approving a
renewed energy plan to help meet the goal.

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Investors Are Once Again Rapidly Minting Early-Stage Startups As
Unicorns
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Through the past couple years, investors have talked about how the
calming of the venture market was good, allowing more time for due
diligence and companies to mature before they sought sky-high
valuations.

Work

What is Y Combinator now? Critics say the famed accelerator is having
an identity crisis
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In December, Y Combinator's first-ever Fall batch got their own Demo
Day. The Silicon Valley-based startup accelerator--which has produced
big hits like Airbnb, Doordash, and Stripe--had doubled the number of
startup classes that could enter its program.

Work

Aura Bora Exits During a Tough Time for Food and Beverage Startups -
Inc (No paywall) [[link removed]}&lead=419599&emailid=146606&nl=daily]
[[link removed]}&lead=419599&emailid=146606&nl=daily]
In the sparkling-water wars of the past decade, few brands have carved
an identity for themselves as clearly as Aura Bora, the six-year-old
brand founded in San Francisco by husband-and-wife team Paul and
Maddie Voge. And few brands have navigated the difficult CPG
fundraising environment of the past two years as confidently as Aura
Bora, which managed to raise $22 million from investors between 2019
and 2024.

Work

Trump blames Ukraine over war with Russia, saying it could have made a
deal
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[[link removed]}&lead=419599&emailid=146606&nl=daily]
Meanwhile, European officials urged the US not to side with Moscow.
Kaja Kallas, the EU high representative for foreign affairs and
security policy, tweeted: “Together with European Foreign Ministers,
I spoke to [US secretary of state Marco Rubio] after his talks in
Riyadh. Russia will try to divide us. Let’s not walk into their
traps. By working together with the US, we can achieve a just and
lasting peace – on Ukraine’s terms.”

Work

Stock market today: S&P 500, Dow, Nasdaq futures hit pause with fresh
tariffs, Fed minutes in focus
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[[link removed]}&lead=419599&emailid=146606&nl=daily]
Oil pushed upwards Wednesday against the backdrop of the
Ukraine-Russia war continuing to cause oil disruptions. Markets are
poised for a quick response to the US-Russian peace talks in an
evolving situation.

Work

Google Play Books purchases on iOS now skirt the App Store's
commission
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[[link removed]}&lead=419599&emailid=146606&nl=daily]
Google has gained permission to sell its e-books and audiobooks
directly to customers through its iOS app, Google Play Books.

Work

'Uber for Armed Guards' Rushes to Market Following the Assassination
of UnitedHealthcare CEO
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[[link removed]}&lead=419599&emailid=146606&nl=daily]
Protector, an app that lets you book armed goons the same way you'd
call for an Uber, is having a viral moment. The app started doing the
rounds on social media after consultant Nikita Bier posted about it on
X. Protector lets the user book armed guards on demand.

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Immigration Fuels Innovation in Science to Make the U.S. More
Competitive
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[[link removed]}&lead=419599&emailid=146606&nl=daily]
In late December 2024 a social media storm erupted after entrepreneur
Elon Musk blasted out support for the iconic H-1B visa. The temporary
work visa has long served as a ticket to jobs in the U.S. high-tech
industry for skilled foreign-born scientists and engineers.

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The Surprising Theory That Explains Modern American Life
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Why don't you move?

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